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Dimethyl Sulfoxide

Dimethyl Sulfoxide
Dimethyl sulfoxide is a highly polar aprotic substance. It occurs as a colourless, viscous liquid, or as colourless crystals that are miscible with water, alcohol, and ether.
Produced in cGMP conditions, Dimethyl sulfoxide enhances the topical penetration of drugs owing to its ability to displace bound water from the stratum corneum; this is accompanied by the extraction of lipids and configurational changes of proteins
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Dimethyl Sulfoxide
Dimethyl Sulfoxide
Primary function
Penetration enhancer
Typical use level
Penetration enhancer: >= 80%
Physical data

  • Density: 1.0955 g/cm³
  • pH (50:50 with water): 8.5
  • Viscosity (dynamic): 2.0 cP at 25°C
  • Boiling point: 189°C
  • Partition coefficient log (octanol/water): - 2.03

Benefits / Claims
Broad solubility and completely miscible in water
High degree of chemical compatibility
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