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Hypromellose
Cellulose, 2- hydroxypropyl methyl ether Hydroxypropyl methyl cellulose (HPMC)
Hypromellose
Hypromellose (HPMC) is widely used in pharmaceuticals formulations. It is described as partly O-methylated and O-(2-hydroxypropylated) cellulose. Hypromellose is available in several grades that can vary in viscosity and extent of substitution. In oral solid forms like tablets, HPMC is primarily used as a binder.
Hypromellose
| Hypromellose | |
|---|---|
| Primary function | Binder |
| Typical use level | Concentrations between 2% and 5% w/w may be used as a binder in wet - granulation and dry - granulation |
| Physical data |
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| Benefits / Claims | Well-recognized material Good stability Soluble in cold water (easy to use in process) Different grades available (flexibility on formulation) |
| Suitable for | Tablet Buccal Chewable Oral Syrup Oral Solutions Lotion Modified Release specials |