Precipitated Calcium Silicate
It is used as a diluent or filler in oral solid formulations. It has a high absorptive capacity and can convert liquid APIs to free flowing powders. In ODT formulations, calcium silicates like FM-1000 act as a disintegration aid thereby reducing the disintegration time
Precipitated Calcium Silicate
| Precipitated Calcium Silicate | |
|---|---|
| Primary function | Filler/ Diluent |
| Typical use level | Disintegrant aid: 5 - 20% Filler: 10 - 80% |
| Physical data |
|
| Benefits / Claims | Can absorb liquids more than 50% by weight. Higher absorptive capacity protects the tablets from moisture uptake. With FM-1000, disintegration time can be reduced and range can be anywhere between 5-30 seconds |
| Suitable for | |