Since their creation as the first commercial carbomers over 50 years ago, carbomer polymers have continued to be the highest quality carbomers on the market. Utilized in pharmaceutical products as rheology modifiers, tablet binders, suspension stabilizers, extended release polymers, mucoadhesive aids, and bioavailability enhancers, carbomer polymers are well known for their versatility and ease of use as pharmaceutical excipients. Products within the carbomer polymer family are chemically similar in that they are all high molecular weight, crosslinked polyacrylic acid polymers. However, these gel forming polymers differ by their chemical crosslinking and can be grouped into the following categories.
Carbomer homopolymers: acrylic acid crosslinked with allyl sucrose or allyl pentaerythritol
Carbomer copolymers: acrylic acid and C10-C30 alkyl acrylate crosslinked with allyl pentaerythritol
Carbomer interpolymers: carbomer homopolymer or copolymer that contains a block copolymer of polyethylene glycol and a long chain alkyl acid ester
- low usage level